产品货号：
Z34071
中文名称：
SMC1A (Phospho-S957)抗体
英文名称：
Anti-SMC1A (Phospho-S957) Antibody (Clone#OTI11E1)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMC1A (Phospho-S957) Antibody (Clone#OTI11E1) |
| 指标别名 | CDLS2;DXS423E;KIAA0178;SB1.8;SMC 1 alpha;SMC 1A;SMC protein 1A;SMC1;SMC1A;SMC1alpha;SMC1L1;SMCB |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SMC1A |
| 克隆号 | OTI11E1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 889-1016 of human SMC1A (NP_006297) produced in E.coli. |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins,SMC3 and either SMC1B or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis,although those complexes at the kinetochore remain.Therefore,the encoded protein is thought to be an important part of functional kinetochores.In addition,this protein interacts with BRCA1 and is phosphorylated by ATM,indicating a potential role for this protein in DNA repair.This gene,which belongs to the SMC gene family,is located in an area of the X-chromosome that escapes X inactivation.Mutations in this gene result in Cornelia de Lange syndrome.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq,Jul 2013] |
| Uniprot ID | Q14683 |
| 基因名全称 | structural maintenance of chromosomes 1A |
| 蛋白名全称 | Structural maintenance of chromosomes protein 1A |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:1000 |
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